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Clinical Chemistry 10: 1087-1097, 1964;
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Clinical Chemistry, Vol 10, 1087-1097, Copyright © 1964 by the American Association for Clinical Chemistry

Simplified Estimation of Leucine Aminopeptidase (LAP) Activity

Robert G. Martinek 1, Louis Berger 2, and Dan Broida 2

1 Division of Laboratories, Chicago Board of Health, Chicago, Ill.
2 Clinical Chemistry Laboratory, Iowa Methodist Hospital, Des Moines, Iowa, and the Research Laboratories, Sigma Chemical Company, St. Louis, Mo.

An accepted colorimetric assay for the end product of the enzymic hydrolysis of L-leucyl-beta-naphthylamide by leucine aminopeptidase in serum and urine has been modified. This modification has been shown to result in enhanced facility of handling large numbers of assays of this enzyme with considerably improved precision.

Submitted on September 24, 1963
Accepted on November 14, 1963




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