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Clinical Chemistry 10: 447-450, 1964;
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Clinical Chemistry, Vol 10, 447-450, Copyright © 1964 by the American Association for Clinical Chemistry

False Positive Reaction Due to Methocarbamol in the Screening Test for Vanilmandelic Acid (VMA)

D. J. Campbell 1, R. Sherbaniuk 1, and J. Rigby 1

1 Biochemistry Division of the Department of Clinical Laboratory Services and the Department of Medicine, University Hospital, Edmonton, Alberta, Canada.

Methocarbamol, a widely prescribed muscle relaxant, gives a positive result for increased vanilmandelic acid excretion with the useful screening test devised by Gitlow for evidence of pheochromocytoma. Evidence for the presence of this drug can be obtained from a positive color reaction with the 5-hydroxyindoleacetic acid test, used in the screening for carcinoid tumor.

Submitted on July 9, 1962






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Copyright © 1964 by the American Association for Clinical Chemistry.