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Clinical Chemistry 10: 781-788, 1964;
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Clinical Chemistry, Vol 10, 781-788, Copyright © 1964 by the American Association for Clinical Chemistry

Improved Quantitation of Cephalin-Cholesterol Flocculation Test

Robert G. Martinek 1, Elvira Vimba 2, and Joseph D. Mann 2

1 Division of Laboratories, Chicago Board of Health, Chicago 10, Ill.
2 Clinical Chemistry Laboratory, Iowa Methodist Hospital, Des Moines, Iowa, and the Clinical Chemistry Laboratory, Butterworth Hospital, Grand Rapids, Mich.

A rapid turbidimetric method for the determination of cephalin-cholesterol flocculation is described. Greater specificity and photometric sensitivity have been achieved along with adequate precision.

The test is standardized with the conventional barium sulfate turbidity standards used for other laboratory procedures. Definition of results in turbidity units is proposed, and photometric standardization of the cephalin-cholesterol emulsion described. The stability of the emulsion is elucidated.

Comparison is made with a previously described quantitative method.

Submitted on July 23, 1963






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Copyright © 1964 by the American Association for Clinical Chemistry.