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Clinical Chemistry 10: 838-844, 1964;
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Clinical Chemistry, Vol 10, 838-844, Copyright © 1964 by the American Association for Clinical Chemistry

Determination of Uric Acid

An Automated Analysis Based on a Carbonate Method

Leonard V. Crowley 1

1 St. Mary's Hospital, Minneapolis, Minnesota.

An automated method is described for the determination of uric acid by a carbonate method. Since uric acid is separated from proteins by dialysis, the loss of uric acid due to protein precipitation in manual methods is avoided. There is no appreciable interference from salicylates, high levels of blood sugar, or ascorbic acid. The method shows an acceptable correlation with the uricase method.

Submitted on September 27, 1963




The following articles in journals at HighWire Press have cited this article:


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HypertensionHome page
J. Sundstrom, L. Sullivan, R. B. D'Agostino, D. Levy, W. B. Kannel, and R. S. Vasan
Relations of Serum Uric Acid to Longitudinal Blood Pressure Tracking and Hypertension Incidence
Hypertension, January 1, 2005; 45(1): 28 - 33.
[Abstract] [Full Text] [PDF]


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ANN INTERN MEDHome page
B. F. Culleton, M. G. Larson, W. B. Kannel, and D. Levy
Serum Uric Acid and Risk for Cardiovascular Disease and Death: The Framingham Heart Study
Ann Intern Med, July 6, 1999; 131(1): 7 - 13.
[Abstract] [Full Text] [PDF]




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Copyright © 1964 by the American Association for Clinical Chemistry.