Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 19: 1049-1052, 1973;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Harrison, J. W.
Right arrow Articles by Shaw, W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Harrison, J. W.
Right arrow Articles by Shaw, W.

Clinical Chemistry, Vol 19, 1049-1052, Copyright © 1973 by the American Association for Clinical Chemistry

Relationships among Urinary Aminoimidazolecarboxamide in Urine and Folate, and Vitamin B12 Concentrations in Serum

J. W. Harrison 1, B. A. Slade 1, and W. Shaw 1

1 Nutritional Biochemistry Section, Center for Disease Control, Health Services and Mental Health Administration, Public Health Service, U. S. Department of HEW, Atlanta, Ga. 30333.

Urinary aminoimidazolecarboxamide (AIC), serum folate, and serum vitamin B12 values were determined in 84 apparently healthy individuals. An automated system for determination of AIC in urine is described. Despite claims to the contrary, we found no evidence of a strong relationship between elevated (e.g., >1.3 µg/mg of creatinine) AIC excretion as reflected in a casual sample of urine and folate or vitamin B12 deficiency. Urinary AIC values ranged from 0.10 to 5.20 µg/mg of creatinine. The mean for the population examined was 1.36 ± 1.02 µg/mg of creatinine.


Key Words: megaloblastic anemia, diagnosis • mass screening of population • automated analysis for AIC normal values • frequency distributions • purine nucleotide biosynthesis • index to 24-h urine collection • AutoAnalyzer

Submitted on May 18, 1973
Accepted on June 14, 1973






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1973 by the American Association for Clinical Chemistry.