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Clinical Chemistry 20: 1364-1365, 1974;
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Clinical Chemistry, Vol 20, 1364-1365, Copyright © 1974 by the American Association for Clinical Chemistry

Formaldehyde Interference with the o-Toluidine Procedure for Glucose

Lawrence W. Bond 1, Anita M. Savaria 1, and Robert B. McComb 1

1 Clinical Chemistry Laboratory, Hartford Hospital, Hartford, Conn. 06115.

Formaldehyde, in the quantities normally used to preserve uric acid—gluose reference quality-control solutions, interferes with glucose analysis of these solutions by the o-toluidine procedure. This effect is enhanced by the uric acid present and is observed with other aldehydes.


Key Words: AutoAnalyzer

Submitted on June 17, 1974
Accepted on July 26, 1974






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Copyright © 1974 by the American Association for Clinical Chemistry.