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Clinical Chemistry 20: 1366-1367, 1974;
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Clinical Chemistry, Vol 20, 1366-1367, Copyright © 1974 by the American Association for Clinical Chemistry

Rapid, Efficient Procedure for Extraction of Drugs for Toxicological Analysis

Hans Ehrsson 1 and Daniel Knapp 1

1 Department of Pharmacology, Medical University of South Carolina, 80 Barre St., Charleston, S. C. 29401.

The method involves extraction of nonionized acidic drugs and iodide ion pairs of amines by column chromatography. A yield of about 90% is obtained for acetylsalicylic acid and amphetamine.


Key Words: column chromatography on Celite

Submitted on May 31, 1974
Accepted on August 1, 1974






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Copyright © 1974 by the American Association for Clinical Chemistry.