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Clinical Chemistry 21: 1663-1666, 1975;
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Clinical Chemistry, Vol 21, 1663-1666, Copyright © 1975 by the American Association for Clinical Chemistry

Measurement of Brain-Specific Creatine Kinase Isoenzyme Activity in Serum

Daniel A. Nealon 1 and Arthur R. Henderson 1

1 Department of Clinical Biochemistry, University Hospital (University of Western Ontario), London, Ontario N6G 2K3 Canada

We further modified a diethylaminoethyl-cellulose column-chromatographic system [Clin. Chem. 21, 392 (1975)] so that it will separate all three serum creatine kinase isoenzymes. The modified system can be used to detect brain-specific creatine kinase isoenzyme in serum after brain surgery


Key Words: brain surgery (craniotomy) • chromatography on DEAE-cellulose

Submitted on May 27, 1975
Accepted on July 2, 1975






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Copyright © 1975 by the American Association for Clinical Chemistry.