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Clinical Chemistry 21: 1970-1975, 1975;
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Clinical Chemistry, Vol 21, 1970-1975, Copyright © 1975 by the American Association for Clinical Chemistry

Sex-Related Patterns in the Profiles of Human Urinary Amino Acids

Henri Dirren 1, Arthur B. Robinson 1, and Linus Pauling 1

1 Linus Pauling Institute of Science and Medicine, 2700 Sand Hill Road, Menlo Park, Calif. 94025.

The urinary amino acid profiles of 79 young women and 72 young men were studied with an automated high-pressure amino acid analyzer. A nonparametric statistical analysis was applied for detecting profile differences related to sex and other variables. A strong sex-related pattern was confirmed and its power for sex determination was evaluated. For the women, profile differences related to the use of oral contraceptives were also discovered and evaluated. No correlation with the menstrual cycle was detected.


Key Words: pattern recognition • diagnostic aid • variation, sources of • screening • column chromatography • statistics

Submitted on April 21, 1975






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Copyright © 1975 by the American Association for Clinical Chemistry.