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Clinical Chemistry 21: 803-824, 1975;
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Clinical Chemistry, Vol 21, 803-824, Copyright © 1975 by the American Association for Clinical Chemistry

The Scope of Mass Spectrometry in Clinical Chemistry

Alexander M. Lawson 1

1 Division of Clinical Chemistry, MRC Clinical Research Centre, Harrow, Middlesex HA1 3UJ, England.

Several aspects of mass spectrometry and gas chromatography—mass spectrometry are reviewed, including ionization methods, repetitive scanning, selected ion monitoring, and stable isotope measurement. I discuss the application of these and other mass spectrometry methods to the investigation of compound classes relevant to clinical chemistry, to the assessment of inborn errors of metabolism, and to clinical studies. The latter include consideration of volatiles in body fluids, respiration and blood gases, stable-isotope applications, clinical toxicology, and drugs.

Submitted on March 17, 1975
Accepted on March 18, 1975




The following articles in journals at HighWire Press have cited this article:


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R. Elin
Instrumentation in clinical chemistry
Science, October 17, 1980; 210(4467): 286 - 289.
[Abstract] [PDF]


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Copyright © 1975 by the American Association for Clinical Chemistry.