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Clinical Chemistry 21: 894-895, 1975;
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Clinical Chemistry, Vol 21, 894-895, Copyright © 1975 by the American Association for Clinical Chemistry

Rate of Decrease in Serum Ethchlorvynol Concentrations after Extreme Overdosage—A Case Study

Donald J. Pochopien 1

1 Dept. of Pathology, Central Community Hospital, 5701 S. Wood St., Chicago, Ill. 60636.

Ethchlorvynol is a commonly abused sedative hypnotic. I report here a seven-day study of serum ethchlorvynol concentrations in a patient who had received an extreme overdose. These concentrations were correlated with the patient’s response to stimuli. Serum ethchlorvynol concentrations were logarithmically related to time, a fact that can be useful in predicting when a patient’s serum ethchlorvynol concentration will return to a therapeutic concentration. In this case the decrease was about 35% per 24 h.

Submitted on February 10, 1975
Accepted on March 17, 1975




The following articles in journals at HighWire Press have cited this article:


Home page
 Hum Exp ToxicolHome page
A.H. Stead and A.C. Moffat
A Collection of Therapeutic, Toxic and Fatal Blood Drug Concentrations in Man
Human and Experimental Toxicology, January 1, 1983; 2(3): 437 - 464.
[Abstract] [PDF]


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Copyright © 1975 by the American Association for Clinical Chemistry.