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Clinical Chemistry 21: 1172-1174, 1975;
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Clinical Chemistry, Vol 21, 1172-1174, Copyright © 1975 by the American Association for Clinical Chemistry

Modification of a Commercially Available Digoxin Radioimmunoassay Kit for Higher Precision

W. J. F. van der Vijgh 1

1 Department of Clinical Pharmacology, Academic Hospital of the Vrije Universiteit, De Boelelaan 1117, Amsterdam, The Netherlands.

The procedure prescribed for the Schwarz/Mann 125Idigoxin kit was modified with regard to pipetting and counting procedure. Incubation time with dextran-coated charcoal was also investigated. The modifications resulted in a significantly higher precision without introduction of a systematic error and the analysis time per eight-tube batch was decreased by 20 min.

Submitted on February 24, 1975
Accepted on April 14, 1975






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Copyright © 1975 by the American Association for Clinical Chemistry.