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Clinical Chemistry 23: 493-503, 1977;
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Clinical Chemistry, Vol 23, 493-503, Copyright © 1977 by American Association for Clinical Chemistry

Use of equilibrated blood for internal blood-gas quality control

ET Leary, CJ Delaney and MA Kenny

We have used equilibrated human blood for blood-gas quality control since 1970. In blood equilibrated 24 h after shedding, gas tensions are stable for 4 to 6 h at 0 to 4 degrees C; each control specimen is analyzed several times during that period to resolve malfunctions, etc. Three-fourths of all errors in gas-tension measurement detected with equilibrated blood were detected with the highest-tension controls. Equilibrated blood controls signal about one error every 14 d on each instrument. For more complete quality control, we supplement analysis of equilibrated blood with other sorts of controls, comparing results obtained by assaying each patient's specimen on two instruments being our most effective adjunct. Such comparisons have identified erroneous assays in 3.9% of the specimens tested. The magnitude of interinstrument discrepancies (random errors) have ranged from 9 to 100% of the appropriate determinations. We use control data derived from equilibrated blood analysis for special management purposes (evaluating instruments, quantitating micro- vs. macro-sampling discrepancies, and decreasing instrument-repair costs).


The following articles in journals at HighWire Press have cited this article:


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 PerfusionHome page
S. Svenmarker, R. Lindholm, S. Haggmark, E. Jansson, and S. Benze
Clinical evaluation of the CDITM System 400 blood gas monitor
Perfusion, January 1, 1994; 9(1): 71 - 76.
[Abstract] [PDF]


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Copyright © 1977 by the American Association for Clinical Chemistry.