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Clinical Chemistry 23: 944-947, 1977;
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Clinical Chemistry, Vol 23, 944-947, Copyright © 1977 by American Association for Clinical Chemistry

Micromethod for measuring hexachlorophene in whole blood by gas-liquid chromatography

WE Dodson, EE Tyrala and RE Hillman

We describe a micromethod for measuring hexachlorophene by use of gas- liquid chromatography with a 63Ni electron capture detector. The procedure requires 100 micronl of blood for extractions of hexachlorophene, and dichlorophene is added as an internal standard. CV is 3.4% over the concentration range of 500 to 1300 microng of hexachlorophene per liter of whole blood. This procedure permits repeated measurements of hexachlorophene in newborns who are being washed with soap containing hexachlorophene.




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Copyright © 1977 by the American Association for Clinical Chemistry.