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Clinical Chemistry, Vol 23, 994-999, Copyright © 1977 by American Association for Clinical Chemistry
GJ Buffone and SA Lewis
We evaluated analytical factors such as antibody specificity, standard materials, and methodology for the measurement of C3. Mancini-type radial immunodiffusion and immunonephelometry were shown to give comparable data if variables other than procedural variables are eliminated. The most significant analytical factors affecting the measurement were antiserum specificity and source of standard material.
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