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Clinical Chemistry 24: 1531-1533, 1978;
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Clinical Chemistry, Vol 24, 1531-1533, Copyright © 1978 by American Association for Clinical Chemistry

Direct non-chromatographic radioimmunoassay of aldosterone: validation of a commercially available kit and observations on age-related changes in concentrations in plasma

SY Tan, R Noth and PJ Mulrow

Human plasma aldosterone can be rapidly, directly, and reliably measured by radioimmunoassay with use of a commercially available anti- aldosterone antibody. With this method, we show that values tend to decrease with advancing age, especially after the sixth decade.


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P. Ye, C. J. Kenyon, S. M. MacKenzie, A. S. Jong, C. Miller, G. A. Gray, A. Wallace, A. S. Ryding, J. J. Mullins, M. W. McBride, et al.
The Aldosterone Synthase (CYP11B2) and 11{beta}-Hydroxylase (CYP11B1) Genes Are Not Expressed in the Rat Heart
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M. van Onna, A. J.H.M. Houben, A. A. Kroon, T. K.A. Wierema, D. Koster, J. M.A. van Engelshoven, and P. W. de Leeuw
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H Matsuoka, P. Mulrow, and C. Li
Beta-lipotropin: a new aldosterone-stimulating factor
Science, July 11, 1980; 209(4453): 307 - 308.
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