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Clinical Chemistry 25: 298-300, 1979;
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Clinical Chemistry, Vol 25, 298-300, Copyright © 1979 by American Association for Clinical Chemistry

Stability of dilute solutions of gentamicin and tobramycin

L Josephson, P Houle and M Haggerty

Dilution of sera containing gentamicin or tobramycin in glass containers results in substantial adsorption of the antibiotic to the surface of the container, which can be prevented if acidic or basic solutions are used to dilute such sera. We describe protocols for radioimmunoassays of gentamicin and tobramycin that include solutions and containers that obviate this problem.




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Copyright © 1979 by the American Association for Clinical Chemistry.