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Clinical Chemistry, Vol 25, 1251-1253, Copyright © 1979 by American Association for Clinical Chemistry
TH Oddie, AH Klein, TP Foley and DA Fisher
We measured concentrations of thyroxine, triiodothyronine, reverse triiodothyronine, thyroxine-binding globulin, and thyrotropin in pooled samples of cord sera from normal newborns. Sera collected in winter contain significantly (p less than 0.05) higher concentrations of the first tour--14.9, 13.4, 9k9, and 7.5%, respectively--than do sera collected in summer; thyrotropin concentrations are similar in samples collected during winter and summer (p greater than 0.05). With storage, the values for the thyronines and thyrotropin decreased progressively at rates between 0.9 and 5.3% per year; those for thyroxine-binding globulin did not change significantly.
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T. Mannisto, H.-M. Surcel, A. Bloigu, A. Ruokonen, A.-L. Hartikainen, M.-R. Jarvelin, A. Pouta, M. Vaarasmaki, and E. Suvanto-Luukkonen The Effect of Freezing, Thawing, and Short- and Long-Term Storage on Serum Thyrotropin, Thyroid Hormones, and Thyroid Autoantibodies: Implications for Analyzing Samples Stored in Serum Banks Clin. Chem., November 1, 2007; 53(11): 1986 - 1987. [Full Text] [PDF] |
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