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Clinical Chemistry 25: 1251-1253, 1979;
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Clinical Chemistry, Vol 25, 1251-1253, Copyright © 1979 by American Association for Clinical Chemistry

Variation in values for iodothyronine hormones, thyrotropin, and thyroxine-binding globulin in normal umbilical-cord serum with season and duration of storage

TH Oddie, AH Klein, TP Foley and DA Fisher

We measured concentrations of thyroxine, triiodothyronine, reverse triiodothyronine, thyroxine-binding globulin, and thyrotropin in pooled samples of cord sera from normal newborns. Sera collected in winter contain significantly (p less than 0.05) higher concentrations of the first tour--14.9, 13.4, 9k9, and 7.5%, respectively--than do sera collected in summer; thyrotropin concentrations are similar in samples collected during winter and summer (p greater than 0.05). With storage, the values for the thyronines and thyrotropin decreased progressively at rates between 0.9 and 5.3% per year; those for thyroxine-binding globulin did not change significantly.


The following articles in journals at HighWire Press have cited this article:


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Clin. Chem.Home page
T. Mannisto, H.-M. Surcel, A. Bloigu, A. Ruokonen, A.-L. Hartikainen, M.-R. Jarvelin, A. Pouta, M. Vaarasmaki, and E. Suvanto-Luukkonen
The Effect of Freezing, Thawing, and Short- and Long-Term Storage on Serum Thyrotropin, Thyroid Hormones, and Thyroid Autoantibodies: Implications for Analyzing Samples Stored in Serum Banks
Clin. Chem., November 1, 2007; 53(11): 1986 - 1987.
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