Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 26: 1745-1747, 1980;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Runckel, D. N.
Right arrow Articles by Swanson, J. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Runckel, D. N.
Right arrow Articles by Swanson, J. R.

Clinical Chemistry, Vol 26, 1745-1747, Copyright © 1980 by American Association for Clinical Chemistry

Effect of dimethyl sulfoxide on serum osmolality

DN Runckel and JR Swanson

Consecutive values for serum osmolality measured in a patient exceeded (548 mOsm) the previously reported pathological range and, indeed, exceeded that generally considered compatible with life. The patient was receiving large amounts of intravenous dimethyl sulfoxide as part of an experimental protocol to control intracranial pressure resulting from trauma. This compound increases serum osmolality linearly with respect to concentration over the range considered therapeutically significant, 0 to 10 mL/L. The mechanism of its effect on osmolality readings is discussed. It does not interfere with any values for those routine measurements made by continuous-flow (SMAC, Technicon).




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1980 by the American Association for Clinical Chemistry.