Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 27: 697-700, 1981;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Crane, L. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Crane, L. J.

Clinical Chemistry, Vol 27, 697-700, Copyright © 1981 by American Association for Clinical Chemistry

Kinetic latex agglutinometry II: a rapid, quantitative assay for factor VIII antigen

LJ Crane

A rapid method for measuring factor VIII antigen in plasma is presented, based upon optical measurement of the rate of agglutination of a stirred suspension of latex particles coated with anti-factor VIII immunoglobulin, when mixed with plasma containing factor VIII antigen. A log-log relationship exists between factor VIII concentration and the reciprocal of the time required for a fixed absorbance change. The assay is rapid, requiring less than 3 min for normal plasma, involves stable reagents, and can be performed with conventional instrumentation. Antigen values in normal plasma a well as plasma from patients with von Willebrand's disease (angiohemophilia) correlate well with values measured by electroimmunoassay or by radioimmunoassay.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by the American Association for Clinical Chemistry.