Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 28: 79-82, 1982;
This Article
Right arrow Full Text (PDF)
Right arrow A correction has been published
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Stroop, S. D.
Right arrow Articles by Greene, H. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Stroop, S. D.
Right arrow Articles by Greene, H. L.

Clinical Chemistry, Vol 28, 79-82, Copyright © 1982 by American Association for Clinical Chemistry

More sensitive flameless atomic absorption analysis of vanadium in tissue and serum

SD Stroop, G Helinek and HL Greene

We describe a sensitive method for the determination of vanadium in biological substances by atomic absorption spectroscopy. By using background correction and pyrolytically coated graphite tubes with flameless apparatus, this vanadium assay has a sensitivity of 65 pg and a detection limit of 30 pg, approximately sixfold more sensitive than previously reported assays involving this technique. The vanadium concentrations have been determined in several biological materials, including bovine liver and human serum. To investigate signal interferences, we have determined vanadium concentrations in matrix solutions containing several elements at physiologically relevant concentrations. Evaluated by the method of standard additions, the vanadium signals are linear with concentration over a range of 3 to 100 micrograms/L. Tissue vanadium concentrations are similar to those previously reported. Serum vanadium concentrations can be determined directly, and we found values ranging from 2.22 to 3.94 micrograms/L in human serum. The improved sensitivity permits the use of sample sizes substantially smaller than previously required.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1982 by the American Association for Clinical Chemistry.