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Clinical Chemistry 28: 707-708, 1982;
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Clinical Chemistry, Vol 28, 707-708, Copyright © 1982 by American Association for Clinical Chemistry

Incidence of gamma-globulin banding in a healthy population by high- resolution electrophoresis

NM Papadopoulos, RJ Elin and DM Wilson

We report the incidence of electrophoretically homogeneous protein bands occurring in the gamma-globulin region in serum samples from 600 healthy adults, as determined with a high-resolution electrophoretic system. One or more electrophoretically homogeneous protein bands of various intensities were detected in the gamma-globulin region of 30 specimens when we used an improved agarose electrophoretic system, and in two specimens when we used a cellulose acetate electrophoretic system. Improvement of the agarose gel electrophoretic system thus enhanced its sensitivity in defining homogeneous protein bands in the gamma-globulin region. The incidence of these bands in a healthy population is approximately 5%.




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Copyright © 1982 by the American Association for Clinical Chemistry.