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Clinical Chemistry 28: 1283-1286, 1982;
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Clinical Chemistry, Vol 28, 1283-1286, Copyright © 1982 by American Association for Clinical Chemistry

Identification and metabolic implication of 1-deoxyglucose (1,5- anhydroglucitol) in human plasma

S Yoshioka, S Saitoh, T Fujisawa, A Fujimori, O Takatani and M Funabashi

1-Deoxyglucose (1,5-anhydroglucitol), a metabolite related to diabetes mellitus, was identified in human plasma by gas-liquid chromatography and by gas-liquid chromatography/mass spectrometry. Plasma polyols were accurately determined with a gas-liquid chromatograph equipped with an all-glass capillary column. The plasma content of 1-deoxyglucose in healthy persons varies with age. Although the precise physiological role of 1-deoxyglucose remains obscure, the method described here for determining the minor polyol components of plasma, as well as the findings of 1-deoxyglucose in the plasma of healthy subjects, may be useful for investigating the metabolic roles of 1-deoxyglucose.


The following articles in journals at HighWire Press have cited this article:


Home page
 Appl. Environ. Microbiol.Home page
N. Yoshida, E. Uchida, T. Katsuragi, and Y. Tani
A Novel NAD-Dependent Dehydrogenase, Highly Specific for 1,5-Anhydro-D-Glucitol, from Trichoderma longibrachiatum Strain 11-3
Appl. Envir. Microbiol., May 1, 2003; 69(5): 2603 - 2607.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
D. Stickle and J. Turk
A kinetic mass balance model for 1,5-anhydroglucitol: applications to monitoring of glycemic control
Am J Physiol Endocrinol Metab, October 1, 1997; 273(4): E821 - E830.
[Abstract] [Full Text] [PDF]


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Copyright © 1982 by the American Association for Clinical Chemistry.