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Clinical Chemistry 29: 696-697, 1983;
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Clinical Chemistry, Vol 29, 696-697, Copyright © 1983 by American Association for Clinical Chemistry

Rapid quantification of C-reactive protein by centrifugal analysis

L Melamies

I describe a rapid, simple immunoturbidimetric method for determining C- reactive protein in serum. With the Instrumentation Laboratory Multistat III microcentrifugal analyzer, quantitative results are obtained automatically after a few minutes of reaction time. Within-run and between-run coefficients of variation ranged from 2.5 to 12.7% at C- reactive protein concentrations of 55 to 69 and 14 to 25 mg/L, respectively, normal values being less than 10 mg/L. Comparison with the commercially available radial immunodiffusion method (y) yields the regression equation y = 1.011x - 2.112 (r = 0.979, n = 100).




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Copyright © 1983 by the American Association for Clinical Chemistry.