Clinical Chemistry, Vol 32, 1028-1028, Copyright © 1986 by the American Association for Clinical Chemistry

Use of Proton Nuclear Magnetic Resonance Spectroscopy in Detection and Study of Organic Acidurias

¹ Academic Unit of Metabolism and Endocrinology, London Hospital Medical College, London, El 1BB, U.K.
² Section of Perinatal and Child Health, MRC Clinical Research Centre, Harrow, Middlesex, HA1 3UJ, U.K.

Vol. 31, p 1797, column 2: The first paragraph under the heading Methylmalonic Aciduria should read: The spectrum (Figure 4) shows two large methylmalonate resonances ascribable to the CH₃ group split by the adjacent CH into a doublet and the CH proton split in turn by the same CH₃ group to give a quartet. All five patients with methylmalonic aciduria so far investigated show as the major signal the characteristic presence of large amounts of methylmalonate in their urine regardless of their clinical status, with some 3-hydroxypropionate also being present. Signals due to ketoaciduria were also evident in some samples.

p 2014: In line seven of column one, the interval should read 16-53 µmol/L.

Vol. 32, p 35: In the last two lines of last full paragraph, "70 °C" should read "-70 °C" and "20 °C" should read "-20 °C."

p 175: In Table 1, "0.20-0.96" should read "0.2-3.96."

p 179: In Figure 2, transpose A with C and B with D.

p 223: The Figure to the right should have accompanied the Letter by Brugués and Sastre.

p 521: Ref. 15 in the paper by Helenius and Tikanoja was omitted: Matsubara G, Kudo K, Kawashita T, Takamura K. Spectrophotometric determination of hydrogen peroxide with titanium 2-(5-bromopyridyl)azo-5-(N-propyl-N-sulfopropylamino)phenol reagent and its application to the determination of serum glucose using glucose oxidase. Anal Chem 1985;57:1107-9.

p 536: The second author is Lothar Siekmann.

See image in the PDF file.