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Clinical Chemistry 32: 1574-1577, 1986;
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Clinical Chemistry, Vol 32, 1574-1577, Copyright © 1986 by American Association for Clinical Chemistry

Emergency screening for ethylene glycol in serum

KW Ryder, MR Glick and SA Jackson

We have exploited the "interference" of ethylene glycol in the Du Pont aca triglyceride method to develop a convenient and rapid screening method for detecting ethylene glycol in serum. Pretreatment of patient's serum with lipase, glycerol kinase, and other cofactors usually added for triglyceride analysis removes triglycerides and glycerol, but not ethylene glycol, from the sample. The aca triglyceride method may then be used to estimate the ethylene glycol concentration in serum.


The following articles in journals at HighWire Press have cited this article:


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 Clin. Chem.Home page
F. Zoppi and K. Maher
Screening Assay for Ethylene Glycol in Serum • Reply.
Clin. Chem., November 1, 1998; 44(11): 2377 - 2377.
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A. F. Eder, C. M. McGrath, Y. G. Dowdy, J. E. Tomaszewski, F. M. Rosenberg, R. B. Wilson, B. A. Wolf, and L. M. Shaw
Ethylene glycol poisoning: toxicokinetic and analytical factors affecting laboratory diagnosis
Clin. Chem., January 1, 1998; 44(1): 168 - 177.
[Abstract] [Full Text] [PDF]


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Copyright © 1986 by the American Association for Clinical Chemistry.