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Clinical Chemistry 32: 1777-1778, 1986;
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Clinical Chemistry, Vol 32, 1777-1778, Copyright © 1986 by American Association for Clinical Chemistry

Urine discoloration after acetaminophen overdose

PM Clark, JD Clark and T Wheatley

Three patients with acetaminophen overdose were observed to have dark- brown urine at an early stage of their illness. Subsequently, acute anuric renal failure and hepatic dysfunction developed in all three. p- Aminophenol was identified by chromatographic and colorimetric methods in the urine of each case and is thought to be responsible for the discoloration.


The following articles in journals at HighWire Press have cited this article:


Home page
 Hum Exp ToxicolHome page
H.M. Blackledge, J. O'Farrell, N.A. Minton, and A.E.M. McLean
The Effect of Therapeutic Doses of Paracetamol on Sulphur Metabolism in Man
Human and Experimental Toxicology, January 1, 1991; 10(3): 159 - 165.
[Abstract] [PDF]


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Copyright © 1986 by the American Association for Clinical Chemistry.