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Clinical Chemistry 34: 1957-1959, 1988;
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Clinical Chemistry, Vol 34, 1957-1959, Copyright © 1988 by American Association for Clinical Chemistry

Nutritional status of patients with acquired immunodeficiency syndrome

CM Huang, M Ruddel and RJ Elin
Clinical Pathology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892.

Nutritional status may be an important factor in the prognosis of morbidity and mortality. We assessed the nutritional status of individuals seropositive for human immunodeficiency virus (HIV) (as confirmed by Western blot) and of patients with AIDS, by determining the concentration in serum of total protein, albumin, prealbumin (transthyretin), and retinol-binding protein. HIV-seropositive individuals showed no significant difference from normal volunteers in values for prealbumin, albumin, and retinol-binding protein. Patients with AIDS showed significantly smaller prealbumin and albumin concentrations than did normal and HIV-positive individuals. There was no significant difference in the concentration of retinol-binding protein among the three groups. The concentration of total serum protein was significantly greater in HIV-positive individuals and in patients with AIDS than in normal individuals. Thus, the nutritional status of patients with AIDS may be a factor for morbidity and mortality.


The following articles in journals at HighWire Press have cited this article:


Home page
 Nutr Clin PractHome page
D. J. Raiten
Nutrition and HIV Infection: A Review and Evaluation of the Extant Knowledge of the Relationship Between Nutrition and HIV Infection
Nutr Clin Pract, June 1, 1991; 6(3_suppl): i - D-1.
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Copyright © 1988 by the American Association for Clinical Chemistry.