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Clinical Chemistry 34: 602-604, 1988;
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Clinical Chemistry, Vol 34, 602-604, Copyright © 1988 by American Association for Clinical Chemistry

An inherited albumin variant with enhanced affinity for the Amerlex thyroxin-analog

NC France, JF Speed and JV Conaglen
Department of Pathology, Waikato Hospital, Hamilton, New Zealand.

We describe two siblings with artefactually increased results for free thyroxin in serum as measured with the Amerlex analog method, despite normal thyroxin transport. The cause of the artefact is identified as a variant albumin with enhanced affinity for the Amerlex thyroxin-analog.




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Copyright © 1988 by the American Association for Clinical Chemistry.