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Clinical Chemistry 7: 504-511, 1961;
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Clinical Chemistry, Vol 7, 504-511, Copyright © 1961 by the American Association for Clinical Chemistry

Estimation of Cholesterol in Small Quantities of Cerebrospinal Fluid

M. F. Sheff 1, M. Denise Gretz 1, and J. B. McMarlin 1

1 Department of Neurology, Pennsylvania Hospital, Philadelphia 7, Pa.

A method is described for the estimation of cholesterol in spinal fluid using the Tschugaeff reaction to produce a pink color proportional to the cholesterol concentration. The reproducibility and accuracy of the method are of a satisfactory order. The authors feel that, providing elementary safety precautions are observed, the method is suitable for the rapid routine estimation of cholesterol in small samples of spinal fluid.

Submitted on December 26, 1960






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Copyright © 1961 by the American Association for Clinical Chemistry.