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Clinical Chemistry 43: 2007-2008, 1997;
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(Clinical Chemistry. 1997;43:2007-2008.)
© 1997 American Association for Clinical Chemistry, Inc.

Letters to the Editor

Acute Bacterial Prostatitis Induces Hematogenous Dissemination of Prostate Epithelial Cells

Frédéric Dumas1, Pascal Eschwège2 and Sylvain Loric1,a

1 Lab. de Biochim. A, Hôpital Necker, 149 rue de Sèvres, 75015 Paris, France ,
2 Service d'Urol., Hôpital de Bicêtre, Le Kremlin-Bicêtre, France
a Author for correspondence.


To the editor:

Although not yet a part of clinical chemical practice, molecular techniques are sensitive tools to detect hematogenous spread of solid tumor cells in cancer and may become routine methods in the coming years (for review, see (1)). Provided that mRNA is expressed exclusively in tumor tissue and not by normal nucleated blood cells, its presence outside the organ identifies already disseminated cells. We have recently found hematogenous spread of prostate epithelial cells during radical prostatectomy (2) as well as during the course of transurethral resection of the prostate (unpublished data). The different mechanisms underlying hematogenous dissemination of cells from prostate gland remain largely unknown. Among the postulated factors . . . [Full Text of this Article]


Acknowledgments


References




The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Cancer Res.Home page
N. Hara, T. Kasahara, T. Kawasaki, V. Bilim, K. Obara, K. Takahashi, and Y. Tomita
Reverse Transcription-Polymerase Chain Reaction Detection of Prostate-specific Antigen, Prostate-specific Membrane Antigen, and Prostate Stem Cell Antigen in One Milliliter of Peripheral Blood: Value for the Staging of Prostate Cancer
Clin. Cancer Res., June 1, 2002; 8(6): 1794 - 1799.
[Abstract] [Full Text] [PDF]


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Copyright © 1997 by the American Association for Clinical Chemistry.