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Clinical Chemistry 43: 2211-2212, 1997;
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(Clinical Chemistry. 1997;43:2211-2212.)
© 1997 American Association for Clinical Chemistry, Inc.

The Clinical Chemist

Compiled by David E. Bruns, Editor (dbruns@aacc.org)



   Reporting Diagnostic Accuracy
 
The following draft of guidelines was presented for comments at the 1997 Annual Meeting of the Council of Biology Editors. Useful advice has been received from editors of medical journals, epidemiologists, and others. We request comments from our readers as we revise the document for dissemination to editors and investigators, who will, we hope, find it useful:


   Toward a Checklist for Reporting of Studies of Diagnostic Accuracy
 
(1997 CBE Meeting, Session E6, D.E. Bruns, E.J. Huth, E. Magid, and D.S. Young; Supported by the International Federation of Clinical Chemistry and the American Association for Clinical Chemistry)

Diagnostic testing is a critical part of modern medicine. Despite the importance of testing for diagnosis, prognosis, and monitoring, the methodology for evaluations of clinical (diagnostic) accuracy of tests has received only modest attention. Recent studies have documented that most published studies of diagnostic accuracy of clinical tests fail to meet (or fail to document adherence to) reasonable methodological standards.

Assessments of diagnostic accuracy of tests are likely to attract increasing attention. Diagnostic testing accounts for 10–25% of healthcare expenditures, and assessment of the diagnostic accuracy of a test is a logical prerequisite to studies of the test's cost-effectiveness.

The Table below is a step toward a checklist for reporting of studies of diagnostic accuracy. It specifically does not . . . [Full Text of this Article]


   Pericardial Access Device: A New Challenge for TDM?
 

   Public Servants Speak Out
 

   Footnotes
 



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Copyright © 1997 by the American Association for Clinical Chemistry.