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Clinical Chemistry 43: 416-417, 1997;
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(Clinical Chemistry. 1999;43:416-417.)
© 1999 American Association for Clinical Chemistry, Inc.

Letters

Serum Cardiac Troponin I, Creatine Kinase (CK), and CK-MB in Early Posttraumatic Rhabdomyolysis

Jean-François Benoist1,2, Claudine Cosson2, Olivier Mimoz1 and Alain Edouard1,a

1 Unité de Réanimation Chirurg.,
2 Service de Biochim. Gén., Univ. de Paris-Sud, Centre Hosp. de Bicêtre, 94275 Le Kremlin Bicêtre, France
a author for correspondence.


To the Editor:

Early diagnosis of posttraumatic cardiac injury is important for patient outcome (1) but a concomitant rhabdomyolysis may impede its detection by biochemical means. Cardiac troponin I (cTnI) might be a useful tool to specifically assess myocardial damage in trauma patients. We report here serum cTnI, creatine kinase (CK), and CK isoenzyme MB measurements in multiple injured patients with rhabdomyolysis.

Successive trauma patients with rhabdomyolysis [CK activity >500 U/L] during the first 24 h after admission were studied in accordance with the Helsinki Declaration. Exclusion criteria were age >55 years, Injury Severity Score (ISS (2)) <16, and history of prior cardiac or renal disease. Patients were considered to have chest trauma when the chest Abbreviated Injury Score (3) was >=2. Electrocardiography and a transesophageal . . . [Full Text of this Article]


Acknowledgments


References




The following articles in journals at HighWire Press have cited this article:


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A. Lavoinne and G. Hue
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Copyright © 1997 by the American Association for Clinical Chemistry.