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Clinical Chemistry 43: 693-694, 1997;
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(Clinical Chemistry. 1997;43:693-694.)
© 1997 American Association for Clinical Chemistry, Inc.

Letters

Serum Selenium in Institutionalized Elderly Subjects and Relation to Other Nutritional Markers

Carmen Gámez1, Dolores Ruiz-López1,a, Reyes Artacho1, Miguel Navarro1, Antonio Puerta2 and Carmen López1

1 Dept. de Nutricion y Bromatol., Facultad de Farmacia, Universidad de Granada, E-18071 Granada, Spain,
2 Policlínica Granada.
a Author for correspondence.


To the Editor:

Nowadays, there is growing interest in the possible relationship between selenium metabolism and the aging process (1). Epidemiological studies show that selenium may have a preventive role in some degenerative diseases such as hepatic cirrhosis, cardiovascular diseases, and some types of cancer (2)(3). However, information on the influence of selenium on aging is contradictory, apart from the fact that the process is not yet well understood.

We determined the serum concentrations of Se in 93 institutionalized elderly people in Granada (Spain) as a short-term indicator of human selenium status and its correlation with nutrient intake. In addition, taking into account the role of Se in oxidation, in metabolic changes in plasma lipids, and as a component of glutathione peroxidase, we examined other biochemical markers, e.g., total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides. We likewise studied leukocyte numbers in blood, as an indicator of risk of disease through infection, and established their correlation with serum Se concentrations.

To quantify serum selenium, we used the hydride generation atomic absorption spectrometry technique previously optimized (4). Daily dietary intake was determined by the 7-day weighed food record, including a day off (5. . . [Full Text of this Article]


References




The following articles in journals at HighWire Press have cited this article:


Home page
 Am. J. Clin. Nutr.Home page
J. Bleys, A. Navas-Acien, S. Stranges, A. Menke, E. R Miller III, and E. Guallar
Serum selenium and serum lipids in US adults
Am. J. Clinical Nutrition, August 1, 2008; 88(2): 416 - 423.
[Abstract] [Full Text] [PDF]


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Copyright © 1997 by the American Association for Clinical Chemistry.