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Clinical Chemistry 43: 1804-1805, 1997;
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(Clinical Chemistry. 1997;43:1804-1805.)
© 1997 American Association for Clinical Chemistry, Inc.

Oak Ridge Poster Sessions

Planar (Bio)Sensors for Critical Care Diagnostics

Paul A. D'Orazio, Thomas C. Maley, Robert R. McCaffrey, Andy C. Chan, Donna Orvedahl, Joe Foos, David Blake, Sue Degnan, John Benco, Chris Murphy, Peter G. Edelman and Hans Ludia

a author for correspondence: fax 508-359-3955, e-mail hans.ludi@chirondiag.com

Advances in planar (bio)sensors have allowed whole-blood diagnostics to be applied in testing close to the patient, resulting in rapid turnaround times, which are especially desirable in critical care settings. Several new technologies and custom chemicals had to be integrated to allow high performance, small sample size, fast response time, and cost-effective devices. (Bio)sensors described below are used for measurement of blood gases, blood electrolytes, glucose, and lactate in point-of-care environments.

Manufacturing of planar thick-film electrodes on ceramic wafers is now done with standard processes yielding precise patterns through the use of ultrapure metals for prolonged use-life under constant polarization. A platinized carbon paste ink has been developed to screen-print the active electrode of the glucose and lactate biosensor (Fig. 1 , top).



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  		Figure 1. Schematics of an amperometric biosensor (top), a planar oxygen sensor (middle), . . . [Full Text of this Article]


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Copyright © 1997 by the American Association for Clinical Chemistry.