Clinical Chemistry
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Clinical Chemistry 45: 316-317, 1999;
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(Clinical Chemistry. 1999;45:316-317.)
© 1999 American Association for Clinical Chemistry, Inc.


Letters

Urinary Free Cortisol Is Not Affected by Short-term Water Diuresis

Martin Fenske

Department of Animal Physiology, NWI, University of Bayreuth, 95440 Bayreuth, Germany, Fax 49-921-552794; E-mail painter@uni-bayreuth.de


To the Editor:

Urinary free cortisol (UFC) has been shown to be a reliable measure of adrenocortical secretion, and it is generally accepted as being an index of the free fraction in the plasma. However, the interpretation of UFC results reportedly can be compromised when the urine volume in patients is considerably increased because a high fluid intake (5 L/day) increases UFC in healthy subjects (1) and UFC was reported to be closely related with the changes in urine volume in women (2). The aim of this work was to determine whether short-term changes in urine volume influence UFC.

I studied 15 volunteers (6 women and 9 men) with normal body mass indexes (23.9 ± 1.9 . . . [Full Text of this Article]


References




The following articles in journals at HighWire Press have cited this article:


Home page
J Gerontol A Biol Sci Med SciHome page
C. A. Rideout, W. Linden, and S. I. Barr
High Cognitive Dietary Restraint Is Associated With Increased Cortisol Excretion in Postmenopausal Women
J Gerontol A Biol Sci Med Sci, June 1, 2006; 61(6): 628 - 633.
[Abstract] [Full Text] [PDF]


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Clin. Chem.Home page
M. Fenske
How Much "Urinary Free Cortisol" Is Really Cortisol during Water Diuresis in Healthy Individuals?
Clin. Chem., June 1, 2004; 50(6): 1102 - 1104.
[Full Text] [PDF]


Home page
Clin. Chem.Home page
P. Putignano, A. Dubini, and F. Cavagnini
Urinary Free Cortisol Is Unrelated to Physiological Changes in Urine Volume in Healthy Women
Clin. Chem., June 1, 2000; 46(6): 879 - 879.
[Full Text] [PDF]




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