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Clinical Chemistry 46: 139-a-140-a, 2000;
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(Clinical Chemistry. 2000;46:139-140.)
© 2000 American Association for Clinical Chemistry, Inc.


Letters

Elution of Hemoglobin {alpha}Montgomery2ßS2 Hybrid Tetramers by the Variant Apparatus

Jonathan S. Kraussa,1

a Address correspondence to this author at: BIH-222B, MCG, Pathology, 1120 15th St., Augusta GA 30912-3620. Fax 706-721-7837; e-mail jkrauss@mail.mcg.edu.

Keith Bures1
Elizabeth Kenimer1

1 Department of Pathology, Section of Clinical Pathology, Medical College of Georgia, Augusta, GA 30912


To the Editor:

Hemoglobin (Hb) Montgomery ({alpha}48 Leu->Arg) is an uncommon variant first reported in 1975 (1). We report here a case of the association of homozygous HbS (ß6 Glu->Val) with this variant identified by the late Dr. T.H.J. Huisman in an 8-year-old black girl with a life-long sickling disorder.

We quantified Hb fractions by cation-exchange HPLC with the VariantTM Hemoglobin Testing System Beta-Thalassemia Short Program (Bio-Rad Diagnostics) (2)(3). The complete blood count . . . [Full Text of this Article]


References




The following articles in journals at HighWire Press have cited this article:


Home page
Clin. Chem.Home page
G. M. Clarke and T. N. Higgins
Laboratory Investigation of Hemoglobinopathies and Thalassemias: Review and Update
Clin. Chem., August 1, 2000; 46(8): 1284 - 1290.
[Abstract] [Full Text] [PDF]




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