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Letters |
Montgomery2ßS2 Hybrid Tetramers by the Variant Apparatus
a Address correspondence to this author at: BIH-222B, MCG, Pathology, 1120 15th St., Augusta GA 30912-3620. Fax 706-721-7837; e-mail jkrauss@mail.mcg.edu.
1 Department of Pathology, Section of Clinical Pathology, Medical College of Georgia, Augusta, GA 30912
To the Editor:
Hemoglobin (Hb) Montgomery (
48 Leu
Arg) is an uncommon
variant first reported in 1975 (1). We report here a case of
the association of homozygous HbS (ß6 Glu
Val) with this variant
identified by the late Dr. T.H.J. Huisman in an 8-year-old black girl
with a life-long sickling disorder.
We quantified Hb fractions by cation-exchange HPLC with the
VariantTM Hemoglobin Testing System
Beta-Thalassemia Short Program (Bio-Rad Diagnostics)
(2)(3). The complete blood count
References
The following articles in journals at HighWire Press have cited this article:
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G. M. Clarke and T. N. Higgins Laboratory Investigation of Hemoglobinopathies and Thalassemias: Review and Update Clin. Chem., August 1, 2000; 46(8): 1284 - 1290. [Abstract] [Full Text] [PDF] |
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