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Plasma Troponin T and Troponin I after Minimally Invasive Coronary Bypass Surgery

¹ Institut für Laboratoriumsmedizin,
² Institut für Anästhesiologie, and
³ Klinik für Herz- und Gefässchirurgie, Deutsches Herzzentrum München, Lazarettstrasse 36, D-80636 Munich, Germany;
^a author for correspondence: fax 0049-89-1218-1013, e-mail braun@dhm.mhn.de

In the last decade, plasma cardiac troponin T (cTnT) and cardiac troponin I (cTnI) have been identified as specific and sensitive markers of myocardial cell injury (1)(2). During most types of cardiac surgery, some degree of myocardial injury regularly occurs that is dependent on multiple factors, such as the type and extent of the surgical procedure, the method of myocardial protection, the preoperative cardiac status of the patient, and the anesthetic procedures (3)(4). In recent years, minimally invasive direct coronary artery bypass grafting (MIDCAB) and off-pump coronary artery bypass grafting (OPCAB) have been introduced as alternative methods to coronary artery bypass grafting (CABG) (5). The potential advantages of MIDCAB and OPCAB arise from the avoidance of cardiopulmonary bypass (CPB) and cardioplegia. CPB always induces a systemic inflammatory response syndrome, and a substantial number of patients develop multiple organ dysfunction. However, there are also disadvantages of MIDCAB and OPCAB, including difficulty of performing the coronary anastomosis on the beating heart, ischemic damage during occlusion of the targeted vessel, and cardiac dislocation or compression to obtain optimal exposure of the vessels on the posterior wall. Currently, only limited data (6)(7)(8)(9) concerning . . . [Full Text of this Article]

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References

The following articles in journals at HighWire Press have cited this article:

				P. V Rao, P. K Hosabettu, S. Dhaded, A. Mathew, J. Punnen, and M. Kanchi Distal Carotid Perfusion in Combined Carotid Endarterectomy and OP-CABG Asian Cardiovasc Thorac Ann, April 1, 2007; 15(2): 164 - 166. [Abstract] [Full Text] [PDF]

				N. Nesher, E. Zisman, T. Wolf, R. Sharony, G. Bolotin, M. David, G. Uretzky, and R. Pizov Strict Thermoregulation Attenuates Myocardial Injury During Coronary Artery Bypass Graft Surgery as Reflected by Reduced Levels of Cardiac-Specific Troponin I Anesth. Analg., February 1, 2003; 96(2): 328 - 335. [Abstract] [Full Text] [PDF]