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Clinical Chemistry 46: 1016-1017, 2000;
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Right arrow Endocrinology and Metabolism
(Clinical Chemistry. 2000;46:1016-1017.)
© 2000 American Association for Clinical Chemistry, Inc.


Letters

Thyroid Function during Pregnancy

R. Swaminathan1

1 St. Thomas’ Hospital, Department of Chemical Pathology, London SE1 7EH, United Kingdom


To the Editor:

Fantz et al (1) describe a case of hyperthyroidism of hyperemesis gravidarum. They discuss the changes in thyroid function during pregnancy and the causes and investigations of hyper- and hypothyroidism during pregnancy. One of the important differential diagnoses is to determine whether the hyperthyroidism is likely to be transient (as in hyperemesis gravidarum) or related to underlying thyroid disease such as Graves disease.

Red cell zinc or red cell carbonic anhydrase (CA1) is useful in this differentiation. The zinc-containing CA1 is inhibited by thyroid hormones, and in hyperthyroidism red cell zinc . . . [Full Text of this Article]


References

Ann M. Gronowski2,a, Samuel Dagogo-Jack3, Corinne R. Fantz2 and Jack H. Ladenson2

2 Department of Pathology, and,
3 Division of Endocrinology, Department of Medicine, Washington University, School of Medicine, Saint Louis, MO 63110
a Address correspondence to this author at: Department of Pathology, Washington University School of Medicine, Box 8118, Saint Louis, MO 63110. Fax 314-362-1461; e-mail gronowski@pathology.wustl.edu.


To the Editor:


References







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