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Letters |
1 St. Thomas Hospital, Department of Chemical Pathology, London SE1 7EH, United Kingdom
To the Editor:
Fantz et al (1) describe a case of hyperthyroidism of hyperemesis gravidarum. They discuss the changes in thyroid function during pregnancy and the causes and investigations of hyper- and hypothyroidism during pregnancy. One of the important differential diagnoses is to determine whether the hyperthyroidism is likely to be transient (as in hyperemesis gravidarum) or related to underlying thyroid disease such as Graves disease.
Red cell zinc or red cell carbonic anhydrase (CA1) is useful in this
differentiation. The zinc-containing CA1 is inhibited by thyroid
hormones, and in hyperthyroidism red cell zinc
References
2
Department of Pathology, and,
3
Division of Endocrinology, Department of Medicine, Washington University, School of Medicine, Saint Louis, MO 63110
a Address correspondence to this author at: Department of Pathology, Washington University School of Medicine, Box 8118, Saint Louis, MO 63110. Fax 314-362-1461; e-mail gronowski@pathology.wustl.edu.
To the Editor:
References
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