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Clinical Chemistry 51: 926-927, 2005; 10.1373/clinchem.2005.048892
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(Clinical Chemistry. 2005;51:926-927.)
© 2005 American Association for Clinical Chemistry, Inc.

Letters to the Editor

N-Terminal pro-B-Type Natriuretic Peptide Concentrations in Mothers just before Delivery, in Cord Blood, and in Newborns

Benjamin Bar-Oz1,a, Achinoam Lev-Sagie2, Ilan Arad1, Lea Salpeter3 and Amiram Nir4

Departments of1 Neonatology2 Obstetrics and Gynecology and 3 Clinical Biochemistry and 4 Pediatric Cardiology Unit, Hadassah and The Hebrew University Medical Center, Jerusalem, Israel

aAddress correspondence to this author at: Department of Neonatology, Hadassah University Hospital, Mount Scopus, PO Box 24035, Jerusalem, Israel. Fax 972-2-5813068; e-mail baroz@hadassah.org.il or bar-oz@md2.huji.ac.il.

The first 20% of the full text of this article appears below.


To the Editor:

The role of the heart as an endocrine organ was established in 1981 by de Bold et al. (1). Usually, in adults, atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are secreted mainly by the cardiac atria and ventricles, respectively (2). Plasma concentrations of these peptides, particularly that of BNP, have been shown to reflect cardiac dysfunction and volume overload in adults and children (3)(4)(5)(6)(7)(8).

There is evidence that these peptides have possible roles during fetal life in the regulation of organogenesis of the heart and the cardiovascular system, in the regulation of blood pressure and water balance in the developing embryo, and in the transition from fetal to extra-uterine life (9). . . . [Full Text of this Article]




The following articles in journals at HighWire Press have cited this article:


Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
A El-Khuffash, D Barry, K Walsh, P G Davis, and E J Molloy
Biochemical markers may identify preterm infants with a patent ductus arteriosus at high risk of death or severe intraventricular haemorrhage
Arch. Dis. Child. Fetal Neonatal Ed., November 1, 2008; 93(6): F407 - F412.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
A. El-Khuffash and E. J Molloy
Are B-type natriuretic peptide (BNP) and N-terminal-pro-BNP useful in neonates?
Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2007; 92(4): F320 - F324.
[Abstract] [Full Text] [PDF]


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