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Handbook of Clinical Laboratory Testing During Pregnancy. Ann M. Gronowski, editor. Totowa, NJ: Humana Press, 2004, 474 pp., $145.00, hardcover (1 CD). ISBN 1-58829-270-3.

Department of Pathology, Stony Brook University, School of Medicine, Stony Brook, NY 11794-8691

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Pregnancy-related testing has a fascinating complexity, largely related to its role as a crystal ball. Tests to predict respiratory distress syndrome range from the artful, laborious chromatography of lipids to clever applications of biophysical techniques such as fluorescence polarization. Hemolytic disease of the newborn is predicted by the classic, nowadays rare technique of scanning spectrophotometry, whereas the notoriously difficult prediction of premature labor is aided by an ultramodern immunoassay. The possibility of fetal trisomy is derived from a panel of biomarkers by use . . . [Full Text of this Article]