Clinical Chemistry
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Clinical Chemistry 53: 794-795, 2007; 10.1373/clinchem.2006.079582
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(Clinical Chemistry. 2007;53:794-795.)
© 2007 American Association for Clinical Chemistry, Inc.

Letters to the Editor

Considerably Reduced Centrifugation Time without Increased Hemolysis: Evaluation of the New BD Vacutainer® SSTTMII Advance

Birger Mensel, Ulrike Wenzel, Markus Roser, Jan Lüdemann and Matthias Naucka

Institute of Clinical Chemistry, and Laboratory Medicine, Ernst Moritz Arndt University, Greifswald, Germany

aAddress correspondence to this author at: Matthias Nauck, University Hospital Greifswald, Institute of Clinical Chemistry and Laboratory Medicine, Ferdinand Sauerbruchstrasse, D-17487 Greifswald, Germany. Fax 49-3834-86-5502; e-mail matthias.nauck@uni-greifswald.de.

The first 20% of the full text of this article appears below.


To the Editor:

Short in-laboratory turnaround time is important, and reducing centrifugation time can shorten this phase of the preanalytical process. The new BD Vacutainer® SSTTMII Advance (Becton Dickinson, article number 367955) has a semisolid, thyxotrophic acrylic gel with chemical composition identical to that of the previous SSTTMII tube. In the new Advance tube, however, the gel has been extended to 1 side of the tube, forming a gel nose with a larger initial contact surface that is supposed to accelerate gel movement during centrifugation to allow shorter centrifugation time (1). We compared gel barrier formation and hemolysis rates of the new Vacutainer SSTTMII Advance under a conventional centrifugation (CC) mode (13 min, 1700g; acceleration and braking time, 55 s) vs an accelerated centrifugation (AC) mode (5 min, 3000g; acceleration and braking time, 39 s) to determine whether this new Vacutainer system allows reduced centrifugation time while maintaining sample quality.

In vitro hemolysis can be caused by mechanical stress inflicted by higher g-forces, which might artificially increase several serum analytes and cause interference in some laboratory assays (2). . . . [Full Text of this Article]






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Copyright © 2007 by the American Association for Clinical Chemistry.