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Clinical Chemistry 53: 1553, 2007; 10.1373/clinchem.2007.087288
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(Clinical Chemistry. 2007;53:1553.)
© 2007 American Association for Clinical Chemistry, Inc.

Letters to the Editor

The Paradox in Translational Medicine

Giuseppe Lippi1,a, Mario Plebani2 and Gian Cesare Guidi1

1 Sezione di Chimica Clinica, Dipartimento di Scienze, Morfologico-Biomediche, Università degli Studi di Verona, Verona, Italy
2 Dipartimento di Medicina Laboratorio, Università di Padova, Padova, Italy

aAddress correspondence to this author at: Istituto di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università degli Studi di Verona, Ospedale Policlinico G.B. Rossi, Piazzale Scuro, 10, 37134 Verona, Italy. Fax 0039-045-8201889; e-mail ulippi@tin.it.

The first 20% of the full text of this article appears below.


To the Editor:

Advances in laboratory sciences have raised expectations of discovery of clinically useful biomarkers, but few such new tests have appeared to date. Hortin et al. (1) highlighted several challenges in the translation of promising markers into clinical laboratory tests. Translational medicine, which is currently defined as the translation of basic research into practical clinical applications, has great potential to develop and deliver new tools that may assist prevention, diagnosis, and treatment of disease (2). In the field of laboratory medicine, the transfer of promising research assays to daily laboratory practice is a challenge that may take several years and involves many sequential processes: development and validation of clinical assays, release of reagents . . . [Full Text of this Article]






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Copyright © 2007 by the American Association for Clinical Chemistry.