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Commentaries |
University of Alabama at Birmingham, Birmingham, AL.
Address correspondence to the author at: University of Alabama at Birmingham, 1825 University Blvd., SHEL 602, Birmingham, AL 35294-2182. Fax 205-996-9113; e-mail rlorenz@uab.edu.
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The gold standard for diagnosis of celiac disease (CD) requires both a duodenal biopsy showing villus blunting, crypt hyperplasia, and increased numbers of intraepithelial lymphocytes (IELs) and a subsequent small intestinal biopsy that shows resolution of these histological findings after the patient is put on a gluten-free diet (1). The development of new serological tests, however,
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