HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Submit an electronic Letter to the Editor about this paper Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Barton, S. H. Articles by Murray, J. A. Search for Related Content PubMed Articles by Barton, S. H. Articles by Murray, J. A. Related Collections Clinical Case Studies

Commentary

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN.

^aAddress correspondence to this author at: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN. e-mail murray.joseph@mayo.edu.

The first 20% of the full text of this article appears below.

Although refractory celiac disease (RCD) is frequently suspected, alternative or additional diagnoses can often explain the patient’s symptoms. First, it is important to carefully review the original diagnosis, especially the biopsy slides and serology. The absence of the specific gene pairs associated with CD risk, DQA1*05:DQB1*02 (DQ2) or DQA1*03:DQB1*0302(DQ8), makes CD unlikely. RCD is categorized into type I (polyclonal phenotype) and type II (clonal expansion of an aberrant intraepithelial T-cell population). The . . . [Full Text of this Article]