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Clinical Case Study |
Department of Pathology and Laboratory Medicine, University of Louisville Hospital, Louisville, Kentucky.
aAddress correspondence to the author at: Department of Pathology and Laboratory Medicine, University of Louisville Hospital, Louisville, Kentucky, 40292. e-mail scholl01@gwise.louisville.edu.
| The first 20% of the full text of this article appears below. |
Understanding of thrombin formation in vivo has been greatly enhanced by the development of a cell-based model of coagulation. In this model, all clotting is initiated by the combination of tissue factor and activated coagulation factor VII (FVIIa). The source of the tissue factor may be extravascular or intravascular. Once initial thrombin is formed,
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