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Clinical Chemistry 54: 1093-1095, 2008; 10.1373/clinchem.2007.102657
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(Clinical Chemistry. 2008;54:1093-1095.)
© 2008 American Association for Clinical Chemistry, Inc.


Letters to the Editor

Acute Variation of Osteocalcin and Parathyroid Hormone in Athletes after Running a Half-Marathon

Giuseppe Lippi1,a, Federico Schena2, Martina Montagnana1, Gian Luca Salvagno1, Giuseppe Banfi3 and Gian Cesare Guidi1

1 Sezione di Chimica ClinicaDipartimento di ScienzeMorfologico-BiomedicheUniversità di Verona, Italy
2 Sezione di Scienze MotorieDipartimento di ScienzeNeurologiche e della Visione Università di Verona, Italy
3 Istituto Galeazzi e Università di Milano Italy

aAddress correspondence to this author at: Sezione di Chimica Clinica, Dipartimento di Scienze, Morfologico-Biomediche, Università degli Studi di Verona, Ospedale Policlinico G.B. Rossi, Piazzale Scuro, 10, 37134, Verona, Italy, Fax 0039-045-8201889, e-mail ulippi@tin.it

The first 20% of the full text of this article appears below.


To the Editor:

Parathyroid hormone (PTH) and osteocalcin (OC) play important roles in bone remodeling and bone metabolism. Although the physiological functions and clinical significance of these markers are well established, the influence of other biological variables aside from diurnal and seasonal variability has been less well investigated(1). Because little information is available on the kinetics of such markers after physical exercise, we measured PTH and OC in 15 athletes performing a half-marathon run. The study population consisted in 15 healthy trained white males, (mean age, 47 years) who had been engaged in specific endurance training for at least 5 years. Participants performed a 21-km, half-marathon run under competition conditions, while equipped with a heart-rate monitor [mean (SE) VO2 max 85% (3%)]. Prior to the race, preexercise baseline fasting blood samples were collected from the volunteers after a 48-h rest from the last training, 30 min before they warmed up for the race. Post exercise samples . . . [Full Text of this Article]







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