AACC 50th Anniversary Retrospective:

Christopher P. Price

The Evolution of Immunoassay as Seen Through the Journal Clinical Chemistry
Clin Chem 1998 44: 2071-2074. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Nils Krone, Adelbert Anton Roscher, Hans Peter Schwarz, and Andreas Braun

Comprehensive analytical strategy for mutation screening in 21-hydroxylase deficiency
Clin Chem 1998 44: 2075-2082. [Abstract] [Full Text] [PDF]  

Laurence Faure-Delanef, Bruno Baudin, Bénédicte Bénéteau-Burnat, Jean-Christophe Beaudoin, Jacqueline Giboudeau, and Daniel Cohen

Plasma concentration, kinetic constants, and gene polymorphism of angiotensin I-converting enzyme in centenarians
Clin Chem 1998 44: 2083-2087. [Abstract] [Full Text] [PDF]  

Michiyo Urata, Machiko Wakiyama, Masanori Iwase, Makoto Yoneda, Sachiko Kinoshita, Naotaka Hamasaki, and Dongchon Kang

New sensitive method for the detection of the A3243G mutation of human mitochondrial deoxyribonucleic acid in diabetes mellitus patients by ligation-mediated polymerase chain reaction
Clin Chem 1998 44: 2088-2093. [Abstract] [Full Text] [PDF]  

Chi T. Hua, John J. Hopwood, Sven R. Carlsson, Ray J. Harris, and Peter J. Meikle

Evaluation of the lysosome-associated membrane protein LAMP-2 as a marker for lysosomal storage disorders
Clin Chem 1998 44: 2094-2102. [Abstract] [Full Text] [PDF]  

Christoph Berndt, Katrin Haubold, Frank Wenger, Brigitte Brux, Joachim Müller, Peter Bendzko, Timo Hillebrand, Eckhard Köttgen, and Jürgen Zanow

K-ras mutations in stools and tissue samples from patients with malignant and nonmalignant pancreatic diseases
Clin Chem 1998 44: 2103-2107. [Abstract] [Full Text] [PDF]  

Jicun Ren, Arve Ulvik, Helga Refsum, and Per Magne Ueland

Chemical mismatch cleavage combined with capillary electrophoresis: detection of mutations in exon 8 of the cystathionine ß-synthase gene
Clin Chem 1998 44: 2108-2114. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Mohammad S. Saedi, Timothy M. Hill, Kristine Kuus-Reichel, Abhay Kumar, Janice Payne, Stephen D. Mikolajczyk, Robert L. Wolfert, and Harry G. Rittenhouse

The precursor form of the human kallikrein 2, a kallikrein homologous to prostate-specific antigen, is present in human sera and is increased in prostate cancer and benign prostatic hyperplasia
Clin Chem 1998 44: 2115-2119. [Abstract] [Full Text] [PDF]  

Anders Helander, Erling Vabö, Klas Levin, and Stefan Borg

Intra- and interindividual variability of carbohydrate-deficient transferrin, -glutamyltransferase, and mean corpuscular volume in teetotalers
Clin Chem 1998 44: 2120-2125. [Abstract] [Full Text] [PDF]  

Thomas G. Rosano, Robert T. Peaston, Henry G. Bone, Henning W. Woitge, Roger M. Francis, and Markus J. Seibel

Urinary free deoxypyridinoline by chemiluminescence immunoassay: analytical and clinical evaluation
Clin Chem 1998 44: 2126-2132. [Abstract] [Full Text] [PDF]  

Stefania Gelmini, Anna Caldini, Lucia Becherini, Sergio Capaccioli, Mario Pazzagli, and Claudio Orlando

Rapid, quantitative nonisotopic assay for telomerase activity in human tumors
Clin Chem 1998 44: 2133-2138. [Abstract] [Full Text] [PDF]  

Dennis L. Broyles, Randall G. Nielsen, Elizabeth M. Bussett, W. Douglas Lu, Isaac A. Mizrahi, Patricia A. Nunnelly, Tram A. Ngo, Julia Noell, Robert H. Christenson, and Barry C. Kress

Analytical and clinical performance characteristics of Tandem-MP Ostase, a new immunoassay for serum bone alkaline phosphatase
Clin Chem 1998 44: 2139-2147. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Peter G. Scheffer, Stephan J. L. Bakker, Robert J. Heine, and Tom Teerlink

Measurement of LDL particle size in whole plasma and serum by high performance gel-filtration chromatography using a fluorescent lipid probe
Clin Chem 1998 44: 2148-2151. [Abstract] [Full Text] [PDF]  

Makoto Hiramatsu, Akio Hayashi, Hideki Hidaka, Hirotsugu Ueshima, and Takashi Kanno

Enzyme immunoassay of urinary mevalonic acid and its clinical application
Clin Chem 1998 44: 2152-2157. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Ekkehard Schütz, Dobrin Svinarov, Maria Shipkova, Paul-Dieter Niedmann, Victor W. Armstrong, Eberhard Wieland, and Michael Oellerich

Cyclosporin whole blood immunoassays (AxSYM, CEDIA, and Emit): a critical overview of performance characteristics and comparison with HPLC
Clin Chem 1998 44: 2158-2164. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Keiichi Imagawa, Yayoi Matsumoto, Yoshito Numata, Atsushi Morita, Shino Kikuoka, Mikio Tamaki, Chie Higashikubo, Tetsuo Tsuji, Kazuyuki Sasakura, Hiroshi Teraoka, Hiroaki Masuzaki, Kiminori Hosoda, Yoshihiro Ogawa, and Kazuwa Nakao

Development of a sensitive ELISA for human leptin, using monoclonal antibodies
Clin Chem 1998 44: 2165-2171. [Abstract] [Full Text] [PDF]  

E. Bissé, N. Zorn, A. Eigel, M. Lizama, P. Huaman-Guillen, W. März, A. Van Dorsselaer, and H. Wieland

Hemoglobin Rambam (ß69[E13]GlyAsp), a pitfall in the assessment of diabetic control: characterization by electrospray mass spectrometry and HPLC
Clin Chem 1998 44: 2172-2177. [Abstract] [Full Text] [PDF]  

Stephen J. Winters, David E. Kelley, and Bret Goodpaster

The analog free testosterone assay: are the results in men clinically useful?
Clin Chem 1998 44: 2178-2182. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

A. P. Shepherd and J. M. Steinke

CO-Oximetry interference by perflubron emulsion: comparison of hemolyzing and nonhemolyzing instruments
Clin Chem 1998 44: 2183-2190. [Abstract] [Full Text] [PDF]  

Phillip Belgrader, William Benett, Dean Hadley, Gary Long, Raymond Mariella, Jr., Fred Milanovich, Shanavaz Nasarabadi, William Nelson, James Richards, and Paul Stratton

Rapid pathogen detection using a microchip PCR array instrument
Clin Chem 1998 44: 2191-2194. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Marta Stahl, Erik D. Lund, and Ivan Brandslund

Reasons for a Laboratory's Inability to Report Results for Requested Analytical Tests
Clin Chem 1998 44: 2195-2197. [Extract] [Full Text] [PDF]  

Julian Diaz, Manuel Fernandez-Arjona, Carmen Perandones, Enrique Serrano, Cristina Frau, Ignacio Cortes, Agustin Luque, and Luis F. Carbonell

Reference Intervals for Biochemistry Parameters for Evaluation of Oxidative Stress in Human Sperm
Clin Chem 1998 44: 2197-2199. [Extract] [Full Text] [PDF]  

Valerian C. Dias, Fiona J. Bamforth, Maria Tesanovic, Matthew E. Hyndman, Howard G. Parsons, and George S. Cembrowski

Evaluation and Intermethod Comparison of the Bio-Rad High-Performance Liquid Chromatographic Method for Plasma Total Homocysteine
Clin Chem 1998 44: 2199-2201. [Extract] [Full Text] [PDF]  

Jacques B. de Kok, Jan C. M. Hendriks, Wouter W. van Solinge, Hans L. Willems, Ewald J. Mensink, and Dorine W. Swinkels

Use of Real-Time Quantitative PCR to Compare DNA Isolation Methods
Clin Chem 1998 44: 2201-2204. [Extract] [Full Text] [PDF]  

Martin Patrick Hughes, Timothy H. Carlson, M. Kathleen McLaughlin, and Daniel D. Bankson

Addition of Sodium Fluoride to Whole Blood Does Not Stabilize Plasma Homocysteine But Produces Dilution Effects on Plasma Constituents and Hematocrit
Clin Chem 1998 44: 2204-2206. [Extract] [Full Text] [PDF]  

Evelyn L. McGown, Kirk Schroeder, and Dean G. Hafeman

Verification of Multichannel Liquid Dispenser Performance in the 4–30 µL Range by Using Optical Pathlength Measurements in Microplates
Clin Chem 1998 44: 2206-2208. [Extract] [Full Text] [PDF]  

Keisuke Eguchi, Yohei Hamaguchi, Yoshimasa Aso, Toshiki Shioiri, Mieko Ogura, and Masato Mitsuhashi

Oligo(dT)-immobilized Pipette Tip: Efficient New Methodology for mRNA Preparation and Direct Gene Amplification
Clin Chem 1998 44: 2208-2210. [Extract] [Full Text] [PDF]  

Vincent Haufroid, André Clippe, Bernard Knoops, Alfred Bernard, and Dominique Lison

Genotyping in Urine: An Interesting Tool for Epidemiological Studies
Clin Chem 1998 44: 2210-2211. [Extract] [Full Text] [PDF]  

Thomas F. Fitzmaurice, Charles Brown, Nader Rifai, Alan H. B. Wu, and Kiang-Teck J. Yeo

False Increase of Cardiac Troponin I with Heterophilic Antibodies
Clin Chem 1998 44: 2212-2214. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Julian Diaz, Enrique Serrano, Francisco Acosta, and Luis F. Carbonell

Reference Intervals for Four Biochemistry Analytes in Plasma for Evaluating Oxidative Stress and Lipid Peroxidation in Human Plasma
Clin Chem 1998 44: 2215-2217. [Extract] [Full Text] [PDF]  

Christian M. Schambeck, Andrea Bedel, and Franz Keller

Limit of Quantification (Functional Sensitivity) of the New IMx Tacrolimus II Microparticle Enzyme Immunoassay
Clin Chem 1998 44: 2217. [Extract] [Full Text] [PDF]  

John D. Johnston and Nicholas J. Miller

Temporal Changes of Serum Antioxidant Concentrations in a Patient with Diabetic Ketoacidosis
Clin Chem 1998 44: 2217-2119. [Extract] [Full Text]  

Johannes van Pelt and Hamid Azimi

False-Positive CDTect Values in Patients with Low Ferritin Values
Clin Chem 1998 44: 2219-2220. [Extract] [Full Text] [PDF]  

Steven M. Faynor and Randy Robinson

Suitability of Plastic Collection Tubes for Cyclosporine Measurements
Clin Chem 1998 44: 2220-2221. [Extract] [Full Text] [PDF]  

Yuh-geng Tsay, Parisa Khosropour, Mark R. Lichtenwalner, Thomas Mencken, and Maria Petosa

Response to a Report on False-Positive Results in a Methadone Enzyme Immunoassay
Clin Chem 1998 44: 2221-2222. [Extract] [Full Text] [PDF]  

K. Wiener, N. B. Roberts, and David B. Sacks

Diagnostic Criteria for Diabetes Mellitus
Clin Chem 1998 44: 2222-2224. [Extract] [Full Text] [PDF]  

Erich E. Fradinger, Gerardo Rodriguez, Cesar Bogado, and Jose R. Zanchetta

Effect of Antiresorptive Therapy on Day-to-Day Variation of Urinary Free Deoxypyridinoline Excretion
Clin Chem 1998 44: 2224-2225. [Extract] [Full Text] [PDF]  

Harald Schennach, Diether Schoenitzer, and Dietmar Fuchs

Association between Chronic Hepatitis C Virus Infection and Increased Neopterin Concentrations in Blood Donations
Clin Chem 1998 44: 2225-2226. [Extract] [Full Text] [PDF]  

Ola Mårtensson, Eva Schink, and Ragnhild Brandt

Diurnal Variability and in Vitro Stability of Carbohydrate-deficient Transferrin
Clin Chem 1998 44: 2226-2227. [Extract] [Full Text] [PDF]  

Maurice J. O'Kane, Ellen C. Allen, and Oliver Grant

Desiccated Coconut as a Quality-Control Material in Fecal Fat Measurements
Clin Chem 1998 44: 2227-2228. [Extract] [Full Text] [PDF]  

Book Reviews:

Demetra Callas

Blood Substitutes: Principles, Methods, Products and Clinical Trials, Vol. 1 and 2.
Clin Chem 1998 44: 2229. [Extract] [Full Text] [PDF]  

Peter Wilding

Molecular Diagnostics for the Clinical Laboratorian.
Clin Chem 1998 44: 2229. [Extract] [Full Text]  

The Clinical Chemist:

The Clinical Chemist
Clin Chem 1998 44: 2230. [Extract] [Full Text] [PDF]  

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