Editorials:

Ulf-Håkan Stenman

New Ultrasensitive Assays Facilitate Studies on the Role of Human Glandular Kallikrein (hK2) as a Marker for Prostatic Disease
Clin Chem 1999 45: 753-754. [Extract] [Full Text] [PDF]  

Daniel W. Chan and Lori J. Sokoll

Prostate-specific Antigen: Advances and Challenges
Clin Chem 1999 45: 755-756. [Extract] [Full Text] [PDF]  

Special Reports:

Michael L. Astion, Sara Kim, Amanda Nelson, Paul J. Henderson, Carla Phillips, Claudia Bien, Lynn Mandel, Adam R. Orkand, and James S. Fine

A Two-Year Study of Microscopic Urinalysis Competency Using the Urinalysis-Review Computer Program
Clin Chem 1999 45: 757-770. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Pieter H. Griffioen, Louwerens Zwang, Ron H.N. van Schaik, Henk Engel, Jan Lindemans, and Christa M. Cobbaert

Optimization of Apolipoprotein(a) Genotyping with Pulsed Field Gel Electrophoresis
Clin Chem 1999 45: 771-776. [Abstract] [Full Text] [PDF]  

Michael C. Little, Jeffrey Andrews, Richard Moore, Silvia Bustos, Lynda Jones, Chris Embres, Gerard Durmowicz, James Harris, Dolores Berger, Karen Yanson, Christine Rostkowski, Daretta Yursis, James Price, Thomas Fort, Adriann Walters, Matthew Collis, Oscar Llorin, Janet Wood, Frank Failing, Christian O'Keefe, Brian Scrivens, Bill Pope, Tim Hansen, Ken Marino, Keith Williams, and Michael Boenisch

Strand Displacement Amplification and Homogeneous Real-Time Detection Incorporated in a Second-Generation DNA Probe System, BDProbeTecET
Clin Chem 1999 45: 777-784. [Abstract] [Full Text] [PDF]  

Susan T. Wingo, Matthew D. Ringel, Jeffrey S. Anderson, Aneeta D. Patel, Yvonne D. Lukes, Yin-Ying Djuh, Barbara Solomon, Diamaud Nicholson, Pina L. Balducci-Silano, Michael A. Levine, Gary L. Francis, and R. Michael Tuttle

Quantitative Reverse Transcription-PCR Measurement of Thyroglobulin mRNA in Peripheral Blood of Healthy Subjects
Clin Chem 1999 45: 785-789. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Margot H. Black, Angeliki Magklara, Christina V. Obiezu, Dimitrios N. Melegos, and Eleftherios P. Diamandis

Development of an Ultrasensitive Immunoassay for Human Glandular Kallikrein with No Cross-Reactivity from Prostate-specific Antigen
Clin Chem 1999 45: 790-799. [Abstract] [Full Text] [PDF]  

George G. Klee, Marcia K. Goodmanson, Steven J. Jacobsen, Charles Y.F. Young, Judith A. Finlay, Harry G. Rittenhouse, Robert L. Wolfert, and Donald J. Tindall

Highly Sensitive Automated Chemiluminometric Assay for Measuring Free Human Glandular Kallikrein-2
Clin Chem 1999 45: 800-806. [Abstract] [Full Text] [PDF]  

Katinka A. Schatteman, Filip J. Goossens, Simon S. Scharpé, Hugo M. Neels, and Dirk F. Hendriks

Assay of Procarboxypeptidase U, a Novel Determinant of the Fibrinolytic Cascade, in Human Plasma
Clin Chem 1999 45: 807-813. [Abstract] [Full Text] [PDF]  

Wan-Ming Zhang, Patrik Finne, Jari Leinonen, Satu Vesalainen, Stig Nordling, and Ulf-HÅkan Stenman

Measurement of the Complex between Prostate-specific Antigen and ₁-Protease Inhibitor in Serum
Clin Chem 1999 45: 814-821. [Abstract] [Full Text] [PDF]  

David J. Newman, Yemi Olabiran, William D. Bedzyk, Suzette Chance, Eileen G. Gorman, and Christopher P. Price

Impact of Antibody Specificity and Calibration Material on the Measure of Agreement between Methods for Cardiac Troponin I
Clin Chem 1999 45: 822-828. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

William L. Roberts, Barun K. De, John P. Coleman, and Thomas M. Annesley

Falsely Increased Immunoassay Measurements of Total and Unbound Phenytoin in Critically Ill Uremic Patients Receiving Fosphenytoin
Clin Chem 1999 45: 829-837. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Kuo-Liong Chien, Yuan-Teh Lee, Fung-Chang Sung, Hsiu-Ching Hsu, Ta-Chen Su, and Ruey S. Lin

Hyperinsulinemia and Related Atherosclerotic Risk Factors in the Population at Cardiovascular Risk: A Community-based Study
Clin Chem 1999 45: 838-846. [Abstract] [Full Text] [PDF]  

Jaap Deinum, Frans H.M. Derkx, and Maarten A.D.H. Schalekamp

Improved Immunoradiometric Assay for Plasma Renin
Clin Chem 1999 45: 847-854. [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Kaj Blomberg, Pertti Hurskainen, and Ilkka Hemmilä

Terbium and Rhodamine as Labels in a Homogeneous Time-resolved Fluorometric Energy Transfer Assay of the ß Subunit of Human Chorionic Gonadotropin in Serum
Clin Chem 1999 45: 855-861. [Abstract] [Full Text] [PDF]  

Steinar Hustad, Per Magne Ueland, and Jørn Schneede

Quantification of Riboflavin, Flavin Mononucleotide, and Flavin Adenine Dinucleotide in Human Plasma by Capillary Electrophoresis and Laser-induced Fluorescence Detection
Clin Chem 1999 45: 862-868. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Jean-Claude Rymer, Robert Sabatier, Alain Daver, Jacques Bourleaud, Marcel Assicot, Jacqueline Bremond, Jacqueline Rapin, Sharon Lynn Salhi, Bruno Thirion, Anne Vassault, Jacques Ingrand, and Bernard Pau

A New Approach for Clinical Biological Assay Comparison and Standardization: Application of Principal Component Analysis to a Multicenter Study of Twenty-One Carcinoembryonic Antigen Immunoassay Kits
Clin Chem 1999 45: 869-881. [Abstract] [Full Text] [PDF]  

Kristian Linnet

Necessary Sample Size for Method Comparison Studies Based on Regression Analysis
Clin Chem 1999 45: 882-894. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Anna Blázovics, Ágota Kovács, Andrea Lugasi, Krisztina Hagymási, Lajos Bíró, and János Fehér

Antioxidant Defense in Erythrocytes and Plasma of Patients with Active and Quiescent Crohn Disease and Ulcerative Colitis: A Chemiluminescent Study
Clin Chem 1999 45: 895-896. [Extract] [Full Text] [PDF]  

Maria Luisa Biondi, Olivia Turri, Dario Dilillo, Giorgio Stival, and Emma Guagnellini

Contribution of the TATA-Box Genotype (Gilbert Syndrome) to Serum Bilirubin Concentrations in the Italian Population
Clin Chem 1999 45: 897-898. [Extract] [Full Text] [PDF]  

Paul A. Seligman and Rhoda B. Schleicher

Comparison of Methods Used to Measure Serum Iron in the Presence of Iron Gluconate or Iron Dextran
Clin Chem 1999 45: 898-901. [Extract] [Full Text] [PDF]  

Iris F.F. Benzie, Wai-yuen Chung, and Brian Tomlinson

Simultaneous Measurement of Allantoin and Urate in Plasma: Analytical Evaluation and Potential Clinical Application in Oxidant:Antioxidant Balance Studies
Clin Chem 1999 45: 901-904. [Extract] [Full Text] [PDF]  

Luisa Alvarez, Josep Oriola, Judith Jo, Teresa Ferró, Francesca Pons, Pilar Peris, Nuria Guañabens, Magdalena Durán, Ana Monegal, M. Jesús Martínez de Osaba, Francisca Rivera-Fillat, and Antonio M. Ballesta

Collagen Type I 1 Gene Sp1 Polymorphism in Premenopausal Women with Primary Osteoporosis: Improved Detection of Sp1 Binding Site Polymorphism in the Collagen Type 1 Gene
Clin Chem 1999 45: 904-906. [Extract] [Full Text] [PDF]  

William L. Roberts, Janelle M. Chiasera, and Kory M. Ward-Cook

Glycohemoglobin Results in Samples with Hemoglobin C or S Trait: A Comparison of Four Test Systems
Clin Chem 1999 45: 906-909. [Extract] [Full Text] [PDF]  

Matthias Nauck, Lioba Glatt, Winfried März, Giso Feussner, and Heinrich Wieland

Simple Precipitation-based Method for the Screening of Type III Hyperlipoproteinemia
Clin Chem 1999 45: 909-911. [Extract] [Full Text] [PDF]  

Book Reviews:

Robert L. Murray

Basic QC Practices. Training in Statistical Quality Control for Healthcare Laboratories. James O. Westgard, Elsa Quam, and Trish Barry. Madison, WI: WesTgard Quality Corporation, 1998, 238 pp., $50.00. ISBN 1-886958-09-2.
Clin Chem 1999 45: 912. [Extract] [Full Text] [PDF]  

Kenneth E. Blick

Reference Information Model for Clinical Laboratories. RILA as a Laboratory Management Toolbox. Henk M.J. Goldschmidt, ed. Amsterdam, The Netherlands: IOS Press, 1998, 261pp., $74.00. ISBN 90-5199-414-1.
Clin Chem 1999 45: 912-913. [Extract] [Full Text]  

Martin Kroll

Tietz Textbook of Clinical Chemistry, Third Edition. Carl A. Burtis and Edward R. Ashwood, eds. Philadelphia, PA: WB Saunders, 1998, 1917 pp., $195.00. ISBN 0-7216-5610-2.
Clin Chem 1999 45: 913-914. [Extract] [Full Text] [PDF]  

Clinical Chemistry Forum:

Donald S. Young and Debra G.B. Leonard

Issues in Genetic Testing
Clin Chem 1999 45: 915-926. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Compiled by David E. Bruns, Editor (dbruns@aacc.org)
Clin Chem 1999 45: 927-928. [Extract] [Full Text] [PDF]  

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