Reviews:

Saeed A. Jortani, James W. Snyder, and Roland Valdes, Jr

The Role of the Clinical Laboratory in Managing Chemical or Biological Terrorism
Clin Chem 2000 46: 1883-1893. [Abstract] [Full Text] [PDF]  

Kay Scouller, Katherine M. Conigrave, Petra Macaskill, Les Irwig, and John B. Whitfield

Should We Use Carbohydrate-deficient Transferrin instead of -Glutamyltransferase for Detecting Problem Drinkers? A Systematic Review and Metaanalysis
Clin Chem 2000 46: 1894-1902. [Abstract] [Full Text] [PDF] Supplemental References  

Minireview:

Y.M. Dennis Lo

Fetal DNA in Maternal Plasma: Biology and Diagnostic Applications
Clin Chem 2000 46: 1903-1906. [Abstract] [Full Text] [PDF]  

Opinion:

Mathias M. Müller

Implementation of Reference Systems in Laboratory Medicine
Clin Chem 2000 46: 1907-1909. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Alberto Batalla, Ruth Alvarez, Julián R. Reguero, Sergio Hevia, Gustavo Iglesias-Cubero, Victoria Alvarez, Arturo Cortina, Pelayo González, Mateo M. Celada, Alfonso Medina, and Eliecer Coto

Synergistic Effect between Apolipoprotein E and Angiotensinogen Gene Polymorphisms in the Risk for Early Myocardial Infarction
Clin Chem 2000 46: 1910-1915. [Abstract] [Full Text] [PDF]  

Henk van Lenthe, André B.P. van Kuilenburg, Tetsuya Ito, Albert H. Bootsma, Arno van Cruchten, Yoshiro Wada, and Albert H. van Gennip

Defects in Pyrimidine Degradation Identified by HPLC-Electrospray Tandem Mass Spectrometry of Urine Specimens or Urine-soaked Filter Paper Strips
Clin Chem 2000 46: 1916-1922. [Abstract] [Full Text] [PDF]  

Boe Sandahl Sørensen, Henrik Schmidt, Hans von der Maase, Per Thor Straten, and Ebba Nexø

Quantification of Melanoma Cell-specific MART-1 mRNA in Peripheral Blood by a Calibrated Competitive Reverse Transcription-PCR
Clin Chem 2000 46: 1923-1928. [Abstract] [Full Text] [PDF]  

Simon J. Clayton, Frank M. Scott, Jill Walker, Kay Callaghan, Kemal Haque, Triantafillos Liloglou, George Xinarianos, Sue Shawcross, Pete Ceuppens, John K. Field, and Jayne C. Fox

K-ras Point Mutation Detection in Lung Cancer: Comparison of Two Approaches to Somatic Mutation Detection Using ARMS Allele-specific Amplification
Clin Chem 2000 46: 1929-1938. [Abstract] [Full Text] [PDF]  

Nicolas von Ahsen, Michael Oellerich, and Ekkehard Schütz

DNA Base Bulge vs Unmatched End Formation in Probe-based Diagnostic Insertion/Deletion Genotyping: Genotyping the UGT1A1 (TA)_n Polymorphism by Real-Time Fluorescence PCR
Clin Chem 2000 46: 1939-1945. [Abstract] [Full Text] [PDF]  

Hemostasis and Thrombosis:

Levente Kárpáti, Botond Penke, Éva Katona, István Balogh, György Vámosi, and László Muszbek

A Modified, Optimized Kinetic Photometric Assay for the Determination of Blood Coagulation Factor XIII Activity in Plasma
Clin Chem 2000 46: 1946-1955. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Santica M. Marcovina, John J. Albers, Angelo M. Scanu, Hal Kennedy, Federico Giaculli, Kåre Berg, Rémy Couderc, Francesco Dati, Nader Rifai, Ikunosuke Sakurabayashi, Jillian R. Tate, and Armin Steinmetz

Use of a Reference Material Proposed by the International Federation of Clinical Chemistry and Laboratory Medicine to Evaluate Analytical Methods for the Determination of Plasma Lipoprotein(a)
Clin Chem 2000 46: 1956-1967. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Karine M. Clauwaert, Jan F. Van Bocxlaer, Els A. De Letter, Serge Van Calenbergh, Willy E. Lambert, and André P. De Leenheer

Determination of the Designer Drugs 3,4-Methylenedioxymethamphetamine, 3,4-Methylenedioxyethylamphetamine, and 3,4-Methylenedioxyamphetamine with HPLC and Fluorescence Detection in Whole Blood, Serum, Vitreous Humor, and Urine
Clin Chem 2000 46: 1968-1977. [Abstract] [Full Text] [PDF]  

Nutrition:

Anthony J. A. Wright, Paul M. Finglas, and Susan Southon

Erythrocyte Folate Analysis: Saponin Added During Lysis of Whole Blood Can Increase Apparent Folate Concentrations, Depending on Hemolysate pH
Clin Chem 2000 46: 1978-1986. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Dieter Ratge, Birgit Scheiblhuber, Maren Nitsche, and Cornelius Knabbe

High-Speed Detection of Blood-borne Hepatitis C Virus RNA by Single-Tube Real-Time Fluorescence Reverse Transcription-PCR with the LightCycler
Clin Chem 2000 46: 1987-1989. [Extract] [Full Text] [PDF]  

Alain Lavoinne, Bruno Cauliez, Hélène Eltchaninoff, René Koning, and Alain Cribier

Analytical and Clinical Performance of the Immulite Cardiac Troponin I Assay
Clin Chem 2000 46: 1989-1990. [Extract] [Full Text] [PDF]  

Steve Wiltshire, Shawn O’Malley, Jeremy Lambert, Kari Kukanskis, David Edgar, Stephen F. Kingsmore, and Barry Schweitzer

Detection of Multiple Allergen-specific IgEs on Microarrays by Immunoassay with Rolling Circle Amplification
Clin Chem 2000 46: 1990-1993. [Extract] [Full Text] [PDF]  

Michael Fahie-Wilson, Penelope Brunsden, John Surrey, and Anthony Everitt

Macroprolactin and the Roche Elecsys Prolactin Assay: Characteristics of the Reaction and Detection by Precipitation with Polyethylene Glycol
Clin Chem 2000 46: 1993-1995. [Extract] [Full Text] [PDF]  

Markus Nauck, Ulrike Stein, Sabine von Karger, Winfried März, and Heinrich Wieland

Rapid Detection of the C3435T Polymorphism of Multidrug Resistance Gene 1 Using Fluorogenic Hybridization Probes
Clin Chem 2000 46: 1995-1997. [Extract] [Full Text] [PDF]  

Michael Vogeser, Dieter Engelhardt, and Karl Jacob

Comparison of Two Automated Adrenocorticotropic Hormone Assays
Clin Chem 2000 46: 1998-2000. [Extract] [Full Text] [PDF]  

Patrick Englebienne, Anne Van Hoonacker, and Joseph Valsamis

Rapid Homogeneous Immunoassay for Human Ferritin in the Cobas Mira Using Colloidal Gold as the Reporter Reagent
Clin Chem 2000 46: 2000-2003. [Extract] [Full Text] [PDF]  

Jacques B. de Kok, Michael R. van Balken, Rian W.H.M. Roelofs, Yvonne A.W.G. van Aarssen, Dorine W. Swinkels, and Jacqueline M.T. Klein Gunnewiek

Quantification of hTERT mRNA and Telomerase Activity in Bladder Washings of Patients with Recurrent Urothelial Cell Carcinomas
Clin Chem 2000 46: 2003-2007. [Extract] [Full Text] [PDF]  

Case Report:

Youri E. Taes, Henk Louagie, Jean-Pierre Yvergneaux, Marc L. De Buyzere, Hendrik De Puydt, Joris R. Delanghe, and John A. Lott

Prolonged Hyperlipasemia Attributable to a Novel Type of Macrolipase
Clin Chem 2000 46: 2008-2013. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Jacques B. de Kok, Michael R. van Balken, Theo J.M. Ruers, Dorine W. Swinkels, and Jacqueline M.T. Klein Gunnewiek

Detection of Telomerase Activity in Urine as a Tool for Noninvasive Detection of Recurrent Bladder Tumors Is Poor and Cannot Be Improved by Timing of Sampling
Clin Chem 2000 46: 2014-2015. [Extract] [Full Text] [PDF]  

Frits A. J. Muskiet, Fey P. L. van der Dijs, M. Rebecca Fokkema, and Fred D. Muskiet

Erythrocyte Folate Does Not Accurately Reflect Folate Status in Sickle Cell Disease
Clin Chem 2000 46: 2015-2016. [Extract] [Full Text] [PDF]  

Stefan Agewall

Increases of Creatine Kinase MB and Cardiac Troponin T in Serum of a Patient with Uterine Leiomyosarcoma
Clin Chem 2000 46: 2016-2017. [Extract] [Full Text] [PDF]  

Ralph Carmel, Shabneet Brar, Atul Agrawal, and P. Daniel Penha

Failure of Assay to Identify Low Cobalamin Concentrations
Clin Chem 2000 46: 2017-2018. [Extract] [Full Text] [PDF]  

Ken Emancipator, Lillian Mansbach, Theresa Robert, and David Waskiewicz

Representatives of Bayer Diagnostics respond:
Clin Chem 2000 46: 2018-2019. [Extract] [Full Text] [PDF]  

Michele L. Turner and Edward P. Acosta

Long-Term Stability of Nelfinavir Mesylate in Human Plasma
Clin Chem 2000 46: 2019-2020. [Extract] [Full Text] [PDF]  

Pascal Kintz, Vincent Cirimele, and Bertrand Ludes

Discrimination of the Nature of Doping with 19-Norsteroids through Hair Analysis
Clin Chem 2000 46: 2020-2022. [Extract] [Full Text] [PDF]  

Michael N. Fahie-Wilson and Rhys John

Detection of Macroprolactin Causing Hyperprolactinemia in Commercial Assays for Prolactin • Dr. John responds:
Clin Chem 2000 46: 2022-2023. [Extract] [Full Text] [PDF]  

Maria Luisa Biondi, Olivia Turri, Simona Leviti, Raffaella Seminati, Federica Cecchini, Mara Bernini, Giorgio Ghilardi, and Emma Guagnellini

MMP1 and MMP3 Polymorphisms in Promoter Regions and Cancer
Clin Chem 2000 46: 2023-2024. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Joseph H. Keffer

Laboratory-Related Measures of Patient Outcomes: An Introduction. Michael G. Bissell, ed. Washington, DC: AACC Press, 2000, 193 pp., $49 ($39 AACC members). ISBN 1-890883-26-3.
Clin Chem 2000 46: 2025-2026. [Extract] [Full Text] [PDF]  

Correction:

S. Neemeshkanna, O. Landt, H.F. Merk, and B. Blömeke

Fluorogenic Probes to Detect the A_-444C Transversion in the Leukotriene C4 Synthase Promoter
Clin Chem 2000 46: 2026. [Extract] [Full Text] [PDF]  

Corrections:

J.M. Davenport and B. Schlain

Testing Claimed Minimal Detectable Concentrations of in Vitro Medical Diagnostic Devices
Clin Chem 2000 46: 2026. [Extract] [Full Text] [PDF]  

National Academy of Clinical Biochemistry:

D. Robert Dufour, John A. Lott, Frederick S. Nolte, David R. Gretch, Raymond S. Koff, and Leonard B. Seeff

Diagnosis and Monitoring of Hepatic Injury. I. Performance Characteristics of Laboratory Tests
Clin Chem 2000 46: 2027-2049. [Abstract] [Full Text] [PDF]  

D. Robert Dufour, John A. Lott, Frederick S. Nolte, David R. Gretch, Raymond S. Koff, and Leonard B. Seeff

Diagnosis and Monitoring of Hepatic Injury. II. Recommendations for Use of Laboratory Tests in Screening, Diagnosis, and Monitoring
Clin Chem 2000 46: 2050-2068. [Abstract] [Full Text] [PDF]  

The Clinical Chemist:

The Clinical Chemist
Clin Chem 2000 46: 2069-2071. [Extract] [Full Text] [PDF]  

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